On January 21, 2025, President Trump withdrew the U.S. from the WHO, citing the organization’s alleged mishandling of COVID-19 and financial disparities. Experts warn this decision could endanger global health initiatives, weaken the U.S.’s pandemic preparedness, and jeopardize significant public health collaborations. WHO Director-General expressed regret and underscored the importance of U.S. participation in global health efforts. Critics argue that the withdrawal undermines the U.S. role in managing health crises worldwide and could have lasting detrimental effects on both national and global health security.