The Kansas City Chiefs secured a 21-7 victory over the Cleveland Browns with Patrick Mahomes throwing two touchdowns before leaving with a left ankle injury. Mahomes was replaced by Carson Wentz as the Chiefs improved to 13-1. The Browns turned the ball over six times, including three interceptions by Jameis Winston. Meanwhile, Ravens quarterback Lamar Jackson threw five touchdown passes in a dominant win against the New York Giants, and multiple teams including the Texans and Bengals also achieved significant victories in Week 15 of the NFL.