Research covering 628 species from 1985 to 2019 indicates that two-thirds of populations examined are experiencing genetic diversity loss, which undermines adaptability to environmental changes. Factors contributing to these declines include habitat loss, climate change, and disease. Notably, actions like re-establishing connectivity among isolated populations can help reverse this trend. Successful conservation examples exist, such as the Florida panther's recovery. The findings emphasize the urgency of global conservation efforts to maintain genetic diversity and ensure species survival amid increasing ecological disturbances.