In a significant escalation of the Syrian civil war, rebels led by Hayat Tahrir al-Sham have taken control of major areas in Aleppo, resulting in over 300 fatalities. The Syrian army has begun retaliatory operations, deploying reinforcements and launching airstrikes on rebel positions. Iranian support for Assad has intensified, further complicating regional dynamics. The conflict's rapid developments raise concerns about humanitarian conditions and regional security, prompting calls for renewed diplomatic efforts to bring about resolution.