Prince Frederik of Luxembourg Dies at 22 from Rare Mitochondrial Disease
Prince Frederik of Luxembourg, aged 22, has passed away after battling POLG mitochondrial disease, a rare genetic condition that affects cellular energy production.
Overview
Prince Frederik of Luxembourg has died at 22 from POLG mitochondrial disease. He was remembered for his humor and compassion, and his work with the POLG Foundation to raise awareness of this rare genetic disorder. His family shared heartfelt tributes, highlighting his strength and positivity while coping with his health challenges. Born in France, Frederik inspired others even in his final moments, asking his father if he was proud of him. The POLG Foundation continues his legacy in searching for treatments for the illness.
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POLG mitochondrial disease is a rare genetic disorder that affects cellular energy production, leading to dysfunction and failure of multiple organs such as the brain, nerves, liver, and muscles. It is caused by mutations in the POLG gene and can present with symptoms like seizures, cognitive regression, and muscle weakness.
Prince Frederik contributed to raising awareness about POLG mitochondrial disease by founding the POLG Foundation, which aims to support treatments and find a cure for the disease. He also played a role in creating the foundation's branding and launched a clothing line to aid research efforts.
Prince Frederik's final interaction with his family involved saying goodbye to each member, including his siblings and cousins, and leaving them with a cherished family joke. He also asked his father if he was proud of him, a moment that was both surprising and profound given his difficulty in speaking.
Prince Frederik's legacy will continue through the POLG Foundation, which he founded to support research and find treatments for POLG mitochondrial disease. His family plans to continue his work, aiming to alleviate suffering for those affected by the disease.
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